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The Relational Sequencing TB Knowledgebase (ReSeqTB) is a one stop source of curated, aggregated, genotypic and phenotypic information and associated metadata from Mycobacterium tuberculosis (Mtb) strains.

The ReSeqTB platform incorporates a standardized, validated whole genome sequencing (WGS) pipeline and a customizable targeted sequence analysis (TSA) pipeline.

The knowledgebase will inform the development of probe-based and next generation sequencing (NGS) assays for interpreting drug resistance / susceptibility and enable large-scale drug resistance surveillance and support clinical decision making for TB patient management.

ReSeqTB provides the content on this website as a free resource to the global TB community. This content has not been evaluated by stringent regulatory authorities and is not intended to be used for patient management.


Dear ReSeqTB users.  We appreciate your support and ReSeqTB have enjoyed hosting your collective data regarding drug resistance for the larger TB community over the last several years.  Unfortunately, we have not been able to secure funding to keep the resource available and updated.  As a result we will need to shut the site down by Q12020.  Please feel free to download existing data for your research projects.  We will be connecting with data contributors separately with next steps regarding their data.  The ReSeqTB platform was transferred to the World Health Organization in 2018 and is being used to support sequencing for the surveillance of drug resistant TB and ultimately the clinical diagnosis of drug-resistant TB.
ReSeqTB Basic Access Site