The Relational Sequencing TB Knowledgebase (ReSeqTB)
is a one stop source of curated, aggregated, genotypic and phenotypic information
and associated metadata from Mycobacterium tuberculosis (Mtb) strains.
The ReSeqTB platform incorporates a standardized, validated whole genome sequencing (WGS)
pipeline and a customizable targeted sequence analysis (TSA) pipeline.
The knowledgebase will inform the development of probe-based
and next generation sequencing (NGS) assays for interpreting
drug resistance / susceptibility and enable large-scale drug resistance surveillance and
support clinical decision making for TB patient management.
ReSeqTB provides the content on this website as a free resource to the global TB community.
This content has not been evaluated by stringent regulatory authorities and is not
intended to be used for patient management.
• 47 additional new graded mutations associated with drug resistance
• 33 additional mutations not associated with drug resistance
• 9 mutations received an upgraded score
• 1 mutation received a downgraded score
• 4 mutations reverted to indeterminant
- Sign up now to access ReSeqTB data, bioinformatics tools, and reports.
- This data contains all curated, aggregated genotypic and phenotypic information for publicly available sequences.
- Visualization and analytic tools available for your use.
- Aggregated data reports of the entire platform can also be downloaded as well as the most recent mutation interpretation table.
- The user only needs a simple registration to access the site.
- Once logged into the public site, links are provided to direct you to the full ReSeqTB platform.
- This platform contains both public data as well as additional limited-access data contributed to the platform.
- This restricted site has limited access set by the contributors.
- Applications to the full-access site is restricted to current CPTR members and ReSeqTB data contributors. Due to the presense of regulated and clinical information, two-factor authentication is required when signing in to the restricted platform for data compliance. Please contact Marco Schito (mschito@c-path.org) if you want to explore access to the private database.
